Heart health supplement development process with ingredient screening, selection using clinical effectiveness, safety, and ease of use criteria, and EVYLO final product bottle
EVYLO comparison table
Heart health supplement comparison chart showing EVYLO ingredients and their clinically supported effects on LDL cholesterol, HDL cholesterol, triglycerides, blood sugar, blood pressure, and blood flow.

Full Transparency: EVYLO's Ingredients

Formulated with clinically studied ingredients at effective doses.

Try EVYLO

Key Ingredients

Berberine

Berberine is a bioactive plant compound extracted from traditional herbs like Berberis aristata (Indian barberry) and Berberis vulgaris (European barberry).

It has been traditionally used as a natural remedy across various cultures, with 3,000+ years of real-life experience.

There are various forms of berberine available, including those that claim improved bioavailability.

Based on our research, the right daily amount for newer forms of berberine hasn’t been well established.

As a result, the amount delivered and absorbed may vary over time, making consistent intake more difficult to ensure.

For this reason, we have chosen a well-studied form of berberine derived from the bark of Berberis aristata—a traditional botanical source that naturally contains berberine alongside a spectrum of complementary compounds, recognized for its long-standing role in supporting heart and metabolic health.

It supports healthy glucose and lipid metabolism, helps maintain insulin sensitivity, and influences key cellular processes involved in how the body produces and uses energy, helping maintain metabolic balance.

BPF® (Bergamot Polyphenolic Fraction)

BPF® (bergamot polyphenolic fraction) is a doctor-developed citrus extract derived from bergamot, a fruit traditionally grown along the coast of Calabria in southern Italy.

Many people recognize bergamot's fragrant oil as the flavor in Earl Grey tea, but the fruit itself is not usually eaten fresh.

Instead, extracts from its juice and peel are used in foods, beverages, and supplements for their potential wellness benefits.

It contains unique flavonoids that help balance cholesterol levels by supporting healthy LDL (“bad cholesterol”), HDL (“good cholesterol”), and triglycerides.

There are many kinds of bergamot extract, but not all are created equal.

Based on our comprehensive review of available human clinical studies, BPF® (bergamot polyphenolic fraction) shows the strongest evidence among commonly studied bergamot extracts for supporting metabolic health in adults.

Developed and studied in Italy—the native region of bergamot—BPF® reflects a research tradition grounded in both scientific rigor and regional expertise, led by a team of medical doctors and PhD scientists.

That is why we chose BPF®—so you can feel confident you’re getting a well-studied form of bergamot.

CoQ10

CoQ10 is a naturally occurring antioxidant found in every cell of our body, where it plays a vital role in cellular energy production and supports heart and mitochondrial function.

CoQ10 levels tend to decline with age, which may impact energy metabolism and heart health.

While CoQ10 is present in both plant- and animal-based foods, the amounts are typically low.

For example, it would take 7.3 pounds of boiled soybeans to match the amount of CoQ10 provided in a single EVYLO capsule.

We have chosen to use a form of CoQ10 that has an extensive track record of clinical research supporting its role in daily vitality and sustained cellular energy.

This ensures you receive a stable, consistent ingredient derived from a method used in decades of scientific study.

Folic Acid

Folic acid is a form of vitamin B9 that plays a key role in heart health by helping to regulate homocysteine levels, an amino acid linked to heart function.

It also supports the formation of red blood cells and contributes to overall vascular health.

While vitamin B9 is naturally present in various plant- and animal-based foods in the form of folate, obtaining enough from food alone to support long-term heart health can sometimes be difficult.

For example, it would take about 11 cups of raw spinach (30 g per cup)—a rich source of folate—to equal the amount of folic acid found in a single EVYLO capsule.

We have chosen to use a well-characterized form of folic acid, as it is precisely measured using the Dietary Folate Equivalents (DFE) unit.

This alignment allows us to deliver a consistent serving every time, ensuring you receive a widely studied ingredient backed by decades of global research to support your daily wellness goals.

*DFE is the FDA-recognized unit that accounts for differences in the absorption of natural food folate and folic acid.

Other Ingredients

Veggie Capsule (Hypromellose)

A plant-derived shell used to house the ingredients.

The capsules we use are Non-GMO Project Verified and suitable for both vegetarians and vegans.

Silicon Dioxide

A naturally occurring mineral found in many plant-based foods.

In supplements, it’s used to prevent the powder from clumping together, helping ensure each capsule is filled evenly and consistently.

Organic Rice Extract Blend (Nu-MAG®)

This USDA Organic, Non-GMO Project Verified, plant-based blend consists of organic rice extract, organic rice hulls, organic gum arabic, and organic sunflower oil.

It ensures our botanical powders flow smoothly into each capsule and maintain a consistent filling process without the use of synthetic additives.

Rice Flour

A gluten-free ingredient made from ground rice that has been used for centuries.

It serves a functional purpose as a filler to ensure the key ingredients precisely fill each capsule, providing a consistent serving size.

Your Questions, Answered

How Do I Know If EVYLO Is Right for Me?

Most heart health supplements are designed to support just one area. EVYLO is different.

EVYLO is designed for adults seeking support across 2+ heart health areas in one daily formula.

EVYLO contains clinically studied ingredients in effective forms and doses shown to support healthy cholesterol, triglycerides, blood sugar metabolism, blood pressure, and circulation.

For example, if you're looking to support both healthy cholesterol and blood sugar levels, EVYLO may be a good fit.

How Can I Trust the Quality and Purity of EVYLO?

For EVYLO, we take ingredient quality and purity seriously — from the first raw material to the final product you hold in your hand.

1. Science-Backed Ingredients

After a comprehensive review of the science, we included only ingredients with strong, consistent results in multiple human studies — not just what’s popular.

2. Trusted Ingredient Sources

We thoroughly reviewed each supplier’s capabilities and credibility.

Every raw ingredient — even those listed under Other Ingredients — must come with proof of quality (a Certificate of Analysis) to confirm purity, accuracy, and authenticity.

3. Manufactured to Strict, Verified Quality Standards

Every batch of EVYLO is produced in FDA-registered U.S. facilities that are certified and audited for compliance to current Good Manufacturing Practice (cGMP) for supplements and food safety by trusted third-party organizations.

(Note: The FDA inspects only about 5% of U.S. facilities annually, so trusted third-party certifications and audits are essential for true quality assurance)

4. Third-Party Tested & Certified to Industry’s Top Quality Standards

EVYLO is rigorously tested and certified to meet some of the highest standards for quality and purity.

It proudly holds both the NSF Contents Certified and BSCG Certified Drug Free seals — trusted international certifications that confirm EVYLO contains what’s on the label and is free from harmful contaminants and banned substances, verified through rigorous third-party testing.

We estimate that fewer than 5% of supplements in the U.S. have earned either of these certifications.

EVYLO also earned Non-GMO Project Verified status — a widely recognized and trusted independent certification for non-GMO products.

5. Transparency at Every Step

We track every stage — from raw ingredients to the finished product — to guarantee traceability and uncompromising quality.

🌿 What EVYLO Is Free From

  • No artificial colors, flavors, or sweeteners
  • No preservatives
  • Gluten-free

Free from the 9 major U.S. allergens:

  • No Milk (including dairy like cheese, butter, and yogurt)
  • No Eggs
  • No Fish (like salmon, tuna, or cod)
  • No Shellfish (like shrimp, crab, or lobster)
  • No Tree nuts (like almonds, walnuts, or cashews)
  • No Peanuts
  • No Wheat (found in bread, pasta, and baked goods)
  • No Soy (found in soy sauce, tofu, and many processed foods)
  • No Sesame (including sesame seeds, tahini, or sesame oil)

How Long Does It Take to See Results?

If used as directed on the label:

Some people may feel more energized within days or weeks.

More noticeable results may appear within four weeks of daily use.

For best results, we recommend taking EVYLO daily as part of a long-term wellness routine, along with balanced nutrition and regular physical activity.

Individual results may vary based on your unique health history and lifestyle.

Should I Take EVYLO With Food?

For best results, take EVYLO with or just before meals.

As a general precaution based on ingredient interactions, we recommend avoiding grapefruit, grapefruit juice, or alcohol around the time of use.

Can I Take EVYLO With My Medications?

As with any supplement and food, certain ingredients may interact with medications.

EVYLO contains ingredients that may affect how cyclosporine is metabolized.

Hence, we recommend against taking EVYLO if you are on cyclosporin.

Based on our research, we do not expect additional significant interactions.

While we are not aware of other major interactions, everyone's health situation is unique.

We recommend that you speak with your healthcare provider before starting any new supplement — especially if you are taking prescription medications or have pre-existing medical conditions.

Is the Daily Amount Flexible?

The recommended 4-5 capsules daily reflects the full, clinically studied dose of
our ingredients for maximum support across two or more heart health areas.

However, because dietary supplements should complement your individual lifestyle and diet, we always encourage consulting with your healthcare provider to help determine the right daily amount for your personal wellness goals.

Is This a Subscription or a One-Time Purchase?

This is a one-time purchase.

No subscriptions, no auto-shipments, and no recurring charges. What you see at checkout is exactly what you pay.

Do You Offer Refunds If I’m Not 100% Satisfied?

Yes—your purchase is covered by our 90-day money-back guarantee.

Just reach out to our customer care team through our Contact Page and we’ll make it right.

No need to return bottles. No return shipping fees.

What If I Have Any Additional Questions on EVYLO or Our Company in General?

You can visit our full FAQ Page or reach out to our team anytime through our Contact Page.

For our customers, we offer a free 15-minute product support call after your purchase to help you get the most out of your experience.

You’ll receive the scheduling link in your purchase confirmation email.

Note: These support calls are for informational purposes regarding product usage only and do not replace professional medical advice.

  • Hani H

    "At my age, health is a priority and this is good for my daily metabolic support... And most of all, it's vegan!"

  • Jackie P

    "I’ve been taking these for the last week and I have to say I feel like I have more energy."

  • Sylvia W

    "...the appearance of the ingredients are identifiable and that gives me confidence in the product."