“I’m getting older. I want my heart and metabolism to stay strong and balanced as I age. With my background as both a pharmacist and a doctoral healthcare researcher, I understand how profoundly these systems influence long-term health and well-being. Everyone talks about longevity—living not just longer, but better.”

The truth?

It isn’t hidden in a miracle pill—it’s been in plain sight all along, waiting for those willing to understand and apply it.

Decades of rigorous scientific research—including guidance from the American Heart Association—have identified eight essential lifestyle and health factors, known as Life’s Essential 8, that promote optimal heart and metabolic wellness.

Science confirms these eight powerful habits can help support heart health and thus unlock lasting vitality.

They include maintaining healthy levels of cholesterol, blood sugar, and blood pressure.

That awareness motivated me to make meaningful lifestyle changes—and to take a closer look at vitamins and supplements.

But with so many available options—and so much marketing noise—I just felt overwhelmed!

Over the past few years, I’ve spent hundreds of hours conducting a holistic review of scientific evidence to separate the noise from the true signals that matter for heart and metabolic wellness.

Here’s what truly matters in choosing a supplement—and what’s too often missing in the real world.

Formulator transparency.

I want to know who actually formulates a supplement and their qualifications.

That gives me more confidence that the person behind it truly understands what they’re doing.

This is sometimes disclosed, but often not at all.

Scientific evidence.

Consumers rarely see clear, understandable evidence behind products.

Some supplements rely only on early lab or animal research, while others are backed by multiple, well-designed human studies.

We simply can’t know the right dosing for people if the research never reaches humans—and what value am I really gaining if the dose is off?

I might as well just focus on other free lifestyle changes instead.

The difference matters—and when companies either hide their data or overwhelm us with too much, it’s nearly impossible to tell which information is truly meaningful.

The range is huge—and it’s far too time-consuming for an average consumer to sort through.

Some brands say, “I’ve already done the work for you,” and maybe they have—but if nothing’s shared publicly, how would I ever know?

Formulation based on a comprehensive scientific evidence review is incredibly important.

As the body of research grows, we start to see both positive and negative findings—and what truly matters is whether the overall evidence remains consistently positive, how strong the health support appears to be, and whether the results are statistically meaningful.

Unfortunately, many companies cherry-pick studies and don’t give a clear picture of the most important science—something I see far too often.

Evidence-based dosing.

Recommended dosages should align with published scientific data or healthcare guidance.

I see so many different daily dosage recommendations—even for the same health purpose—that it leaves me more puzzled than ever.

If dose doesn’t matter, why am I using supplements? Honestly, it makes me laugh.

Manufacturing quality.

Meeting current good manufacturing practice (cGMP) standards is one of the most important quality indicators for supplements.

Most of us assume we can rely on the FDA to make sure that’s happening.

But the reality is, the FDA’s resources are limited—it inspects only about 5% of supplement manufacturing facilities in the U.S. each year.

That means it could take roughly 20 years to revisit the same facility for another inspection. Shocking, right?

That’s why the next best option is to look for proof that the facilities making a supplement are cGMP-certified by reputable, independent organizations.

Too often, though, I see vague icons like “GMP,” “cGMP,” or “FDA registered,” and I can’t help but wonder—what are you really trying to tell me?

Third-party testing.

Similarly, the FDA advises manufacturers to follow current good manufacturing practice (cGMP) standards—guidelines meant to help ensure that final products contain what’s on the label and are free from unwanted substances or contaminants.

Because FDA surveillance is limited, as noted earlier, the next best safeguard is third-party verification from reputable, independent organizations.

What concerns me is how few supplements actually carry credible third-party quality certifications—only about 4–12% overall.

Outside of core categories like vitamins, minerals, and amino acids, the percentage drops even further: certified products make up roughly one-third as many (<8% vs. 24%).

This matters deeply to me, since heart and metabolic health supplements—the area I care most about—typically fall into that under-certified group.

Some brands do perform their own third-party testing without pursuing official certification, but these tests are often unstandardized and the results rarely shared publicly.

Research has also found that 14–50% of supplements may contain ingredients or contaminants banned by sports authorities such as the World Anti-Doping Agency.

There’s no proof that uncertified or untested supplements are harmful, but I think they carry an unnecessary long-term risk—one I’d rather avoid.

Comprehensive heart and metabolic support.

I’ve been searching for supplements that provide well-rounded support across key areas of heart and metabolic wellness—things like cholesterol balance (LDL and HDL), triglycerides, blood sugar, blood pressure, and overall circulation.

Yet most of the products I’ve come across only target one or two of these areas, leaving the rest unaddressed.

After all that research, I came to a simple realization: the best path forward was to create what I couldn’t find—a supplement built from the ground up to meet the highest scientific, quality, and manufacturing standards, focusing solely on what truly supports heart and metabolic wellness.

Following more than 1,000 hours of research and development across 18 months, EVYLO came to life—a product built on uncompromising quality and unwavering authenticity.

It’s given me the confidence I was looking for.

Spending just 30 seconds a day taking it, I’ve noticed meaningful changes—I feel better and see positive trends across the health data I track for myself.

My sincere hope is that others seeking comprehensive support for their heart and metabolic health can experience the same trust and peace of mind.

Because when our health feels steady, life opens up—exploring new places, building our careers, being present with the people we love, and savoring the small moments that make life meaningful.

— Derek Tang, PhD, MS, BSPharm

Founder and Advisor